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(Registered UK company)

 

UK based DMPK Consultancy: 

For small molecules, DMPK is crucial.  
 
Pharmacokinetics, efficacy, drug-drug interactions and toxicity can all be driven by how a drug is metabolised and transported across membranes.

A rigorous understanding of DMPK parameters and IVIVE will streamline lead optimisation and candidate selection and guide the potential complexity of your IND/CTA roadmap to clinical development. 

DMPK Services Ltd, provides expert DMPK and pre-clinical IND consultancy - including ADME, In vitro studies, IVIVE (Cl, exposure vs target, early Dose-2-Man prediction etc), DDI, MIST, DILI, early de-risking strategies and Discovery: 

+ Outsourcing Management:

      - Study design(s)

      - Data/report review

      - Cost builds

      - Study monitoring

      - Facility/SOP review
 

+ Custom radiosynthesis

    - choice of isotope

    - position of labelling

    - quantity required

    - maximizing its use


 

+ IND/CTA program design

     - IB review

     - Roadmap/Gap analysis

     - Regulatory advice
 

+ DMPK Service Area Overview

      - ADME

      - DDI

      - PK

 

CONTACT

 

Feel free to contact me without obligation using either my direct email or via the contact box in the menu.

Email:   Guy.webber@dmpkservices.com

Or connect and message me on LinkedIn:  https://www.linkedin.com/in/guywebber/

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